Ubiquinol is the active antioxidant form of CoQ10.
It has an additional 2 hydrogen atoms and compromises the majority of the ubiquinone/ubiquinol pool in the plasma of healthy subjects.
Ubiquinol may be especially important for older individuals, individuals who may be experiencing greater levels of oxidative or physical stress, or individuals who appear not to respond to regular CoQ10supplementation (possibly due to poor conversion of CoQ10to ubiquinol in the body).
In a preliminary case report involving an open clinical evaluation using ubiquinol, a U.S. cardiologist reports that plasma CoQ10levels doubled for one 52-year-old woman after supplementation with 300 mg ubiquinol in divided doses for 1 month.
It was also noted that ubiquinol supported a healthy ratio of CoQ10to lipids.